Figure 1.

Study design. A three-step approach was applied. Step 1 served in the identification of the minimal myeloid cell variable core. Step 2 comprised the quantification of the myeloid cell variables in the development set samples and the definition of the MIS by adaptive index modeling. In step 3, the MIS was validated in the validation set samples. MDSC, myeloid-derived suppressor cells; MIS, myeloid index score.