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Hydrogel-based 3D matrix for studying cancer cell invasion
(A) The invasion of cancer cells into collagen gel elicits proteolytic activity of cancer cells. (Reproduced with permission from (Wolf and Friedl, 2009)).
(B) An ECM mimicking system with tunable plasticity formed by basement membrane proteins and alginate cross-linking network. (Reproduced with permission from (Wisdom et al., 2018))
