. 2021 Feb 5;7(2):e06195. doi: 10.1016/j.heliyon.2021.e06195

Table 3.

Effect of antioxidant potent extract (EAE) of U. dioica on PTZ-induced seizure.

Groups	Myclonic jerk (s)		Tonic generalized extensor (s)		Generalized clonic seizure (s)
Groups	Onset	Duration	Onset	Duration	Onset	Duration
Vehicle control	76.79 ± 6.71	42.33 ± 2.53	164.74 ± 3.82	20.61 ± 1.68	287.34 ± 8.37	32.71 ± 2.15
DZP (4 mg/kg, i.p.)	0.0^a	0.0^a	0.0^a	0.0^a	0.0^a	0.0^a
EAE (50 mg/kg, p.o.)	124.79 ± 13.24^a	18.46 ± 1.73^a	212.22 ± 11.41^a	9.83 ± 1.83^a	386.85 ± 10.19^a	12.43 ± 2.58^a
EAE (100 mg/kg, p.o.)	285.67 ± 23.60^a,b	7.33 ± 1.03^a,b	338.72 ± 8.76^a,b	7.03 ± 4.67^a,b	415.46 ± 4.34^a,b	8.47 ± 4.85^a,b
EAE (200 mg/kg, p.o.)	337.9 ± 15.32^a,b,c	5.46 ± 2.03^a,b,c	414.40 ± 8.34^a,b,c	5.08 ± 3.58^a,b,c	510.22± 6.67^a,b,c	5.65 ± 3.92^a,b,c

Results are expressed as mean ± SEM; (n = 6). ^a p < 0.05 vs VC; ^b p < 0.05 vs EAE 50 mg/kg; ^c p < 0.05 vs EAE 100 mg/kg; Statistical analysis done by one-way ANOVA followed by multiple comparisons Dunnett's test.