. 2021 Feb 5;7(2):e06195. doi: 10.1016/j.heliyon.2021.e06195

Table 4.

Effect of antioxidant potent extract (EAE) of U. dioica on MES-induced convulsions.

Groups	No. of animal showing THLE	Various phases of convulsions (s)
Groups	No. of animal showing THLE	Flexion (sec.)	Extension (sec.)	Clonus	Stupor	% Protection against THLE
Vehicle control	6/6	3.16 ± 0.75	9.50 ± 0.54	17.16 ± 0.98	27.37 ± 0.34	0
PHT (25 mg/kg, i.p.)	0/6	1.50 ± 0.54^a	2.30 ± 0.51^a	3.50 ± 0.51^a	10.64 ± 0.23^a	100^a
EAE (50 mg/kg, p.o.)	3/6	2.60 ± 0.81^a	6.50 ± 1.04^a	9.65 ± 0.89^a	24.56 ± 0.87^a	50.00^a
EAE (100 mg/kg, p.o.)	4/6	2.50 ± 0.54^a,b	4.80 ± 0.75^a,b	8.43 ± 0.81^a,b	20.73 ± 0.45^a,b	66.66^a,b
EAE (200 mg/kg, p.o.)	1/6	2.10 ± 0.40^a,b,c	3.00 ± 0.89^a,b,c	6.85 ± 0.81^a,b,c	16.86 ± 0.50^a,b,c	83.33^a,b,c

Results are expressed as Mean ± SEM (n = 6); ^a p < 0.05 vs VC; ^b p < 0.05 vs EAE 50 mg/kg; ^c p < 0.05 vs EAE 100 mg/kg; Statistical analysis done by one-way ANOVA followed by multiple comparisons Dunnett's test.