Table 1.

Clinical data (Case 1 and 2)

Findings	Patient 1	Patient 2
Age/sex	9 years/M	7 months/F
Family history of epilepsy	Absent	Absent
Parental consanguinity	Absent	Present
Age at seizure onset	8 years	6 months
IQ	77	Not done
Dysmorphic Features	Synophrys, small posteriorly placed ears	Frontal bossing, epicanthal fold, open mouth, large pinna, microcephaly
MRI Brain	Normal	Widened bilateral frontal and anterior temporal sub arachnoids CSF spaces with deepened Sylvian fissure
Seizure history	GTCS, staring episodes	Focal hypomotor seizures and GTCS
Number of AED tried	4	5
Current AED	VPA, CLB	LVX, TPM, CLB
r(20) Mosaicism in lymphocytes	12%	100%

VPA: Valproate; CLB: Clobazam; LVX: Levetiracetam, TPM: Topiramate