Table 1.

Diagnosis of Takayasu arteritis and giant cell arteritis using the American College of Rheumatology 1990 criteria

Takayasu arteritis∗	Giant cell arteritis†
Age at disease onset ≤40 y •Development of symptoms or findings related to Takayasu arteritis at ≤40 y of age	Age at disease onset ≥50 y •Development of symptoms or findings beginning at ≥50 y of age
Claudication of extremities •Development and worsening of fatigue and discomfort in muscles of one or more extremities while in use, especially the upper extremities	New headache •New onset of or new type of localized pain in the head
Decreased brachial artery pulse •Decreased pulsation of one or both brachial arteries	Temporal artery abnormality •Temporal artery tenderness to palpation or decreased pulsation unrelated to arteriosclerosis of cervical arteries
Blood pressure difference >10 mm Hg •Difference of >10 mm Hg in systolic blood pressure between arms	Elevated erythrocyte sedimentation rate •Erythrocyte sedimentation rate ≥50 mm/h by the Westergren method
Bruit over subclavian arteries or aorta •Bruit audible on auscultation over one or both subclavian arteries or abdominal aorta	Abnormal artery biopsy findings •Biopsy specimen with artery showing vasculitis characterized by a predominance of mononuclear cell infiltration or granulomatous inflammation usually with multinucleated giant cells
Arteriographic abnormality •Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities not due to arteriosclerosis, fibromuscular dysplasia, or similar causes; changes usually focal or segmental

^∗The presence of three or more criteria is consistent with a diagnosis of Takayasu arteritis with sensitivity of 90.5% and specificity of 97.8%.

^†The presence of three or more criteria is consistent with the diagnosis of giant cell arteritis with sensitivity of 93.5% and specificity of 91.2%.

Adapted from Arend et al.⁸ and Hunder et al.⁹