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. 2021 Feb 2;99(2):skab030. doi: 10.1093/jas/skab030

Table 2.

Percent change (+/–) in milk output from day 0 to 28 after farrowing and the maximum variable cell loss rate relative to the reference (Ref) output as the response to changes in individual input parameters from the Ref parameterization (–60%, –30%, +30%, and +60%)

Ref. input Unit –60% –30% 30% 60%
Milk output from day 0 to 28, kg/d (Ref. output: 31.8 kg/d) Kg/d % Change of Ref.
 Hormone decay rate kH 2.45 %/d 1 0 0 −1
 Maximum cell proliferation rate vm 1 cell divisions/d −49 −16 8 21
 Fractional basal cell loss rate ks 10 %/d 9 5 −6 −14
 Fractional variable cell loss rate ksM 58 %/d 2 1 −1 −1
 Michaelis–Menten constant of variable cell loss rate Mh-p 0.9 g/g −71 −17 4 4
 Time period of average kr 2 d 0 0 0 0
 Maximum milk synthesis rate kM 0.21 g milk/1,000 cells/min −44 −9 −2 −7
 Ejectable milk storage capacity Mm-p 11 g milk/1,000 cells −60 −17 7 11
 Maximum milk removal rate rm 150 g milk/min −62 −29 20 28
 Nursing interval t interval 50 min 39 30 −25 −41
 Milk ejection duration t duration 22.5 s −69 −33 22 29
Maximum variable cell loss rate, cells/min (Ref. output: 0.137 cells/min) Cells/min % Change of Ref.
 Hormone decay rate kH 2.45 %/d 13 7 −7 −13
 Maximum cell proliferation rate vm 1 cell divisions/d −99 −80 110 231
 Fractional basal cell loss rate ks 10 %/d 197 86 −57 −86
 Fractional variable cell loss rate ksM 58 %/d −36 −15 11 20
 Michaelis–Menten constant of variable cell loss rate Mh-p 0.9 g/g 239 121 −79 −97
 Time period of average kr 2 d −4 −2 2 4
 Maximum milk synthesis rate kM 0.21 g milk/1,000 cells/min −100 −91 53 84
 Ejectable milk storage capacity Mm-p 11 g milk/1,000 cells 89 7 −3 −6
 Maximum milk removal rate rm 150 g milk/min 214 99 −73 −96
 Nursing interval t interval 50 min −99 −91 54 90
 Milk ejection duration t duration 22.5 s 242 110 −78 −97