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. 2021 Feb 12;12:2041731420978327. doi: 10.1177/2041731420978327

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 7. — Ascorbate, insulin or growth factor supplementation did not increase human or ovine sheet perforation force. Strength of human (a) and ovine (b) sheets produced over 8 weeks with concentrations of ascorbate different than the “standard” 0.5 mM (means ± SD, n = 3–6). One-way ANOVA (* statistically different from 0.25 mM, # statistically different from 0.50 mM, and $ statistically different from 0.75 mM). One representative experiment out of three. Strength of human (c) and ovine (d) sheets produced with their optimal serum supplemented with insulin (means ± SD, n = 3–6). One representative experiment out of three. (e) Strength of ovine sheets produced with growth factor supplementation (means ± SD, n = 5–6). No strength increases were achieved (* statistically different from 0 ng.mL^–1). One-way ANOVA. One representative experiment out of three. Statistical differences were expressed as followed: *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.