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. 2021 Feb 8;20:1533033821990090. doi: 10.1177/1533033821990090

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — FGD5-AS1 knockdown impeded tumorigenesis of non-small cell lung cancer (NSCLC) cells by regulating the miR-944/MACC1 axis. (A) The transfection efficiency of pcDNA-NC and pcDNA-MACC1 was demonstrated using qRT-PCR in A549 cells. ^**P < 0.01 vs. pcDNA-NC; (B-D) Overexpression of MACC1 or inhibition of miR-944 reversed the inhibitory effects of FGD5-AS1 knockdown on viability, migration, and invasion of A549 cells. ^**P < 0.01 vs. sh-NC; ^##P < 0.01 vs. sh-FGD5-AS1 -1. (E) Relative protein levels of Bax and Bcl-2 in A549 cells were detected by western blot. ^**P < 0.01 vs. sh-NC; ^##P < 0.01, ^#P < 0.05 vs. sh-FGD5-AS1 -1.