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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Cancer Causes Control. 2021 Jan 18;32(3):299–309. doi: 10.1007/s10552-020-01384-z

Table 2.

Multivariable adjusted associations between race/ethnicity and circulating biomarkers of CA125 and CA15.3, NHANES 2001–2002.

a) CA125 b) CA15.3
Predictors Average % differences (95%CI) p-value Predictors Average % Differences (95%CI) p-value
Non-Hispanic white ref Non-Hispanic white ref
Non-Hispanic black −29.0 (−42.5, −12.2) 0.004 Non-Hispanic Black 17.3 (−0.5, 38.3) 0.06
Mexican American −6.4 (−18.1, 6.9) 0.3 Mexican American 1.3 (−19.0, 26.7) 0.9
Age, years 0.7 (0.2, 1.2) 0.006 Age, years −0.2 (−1.0, 0.5) 0.42
BMI, kg/m2 0.4 (−1.4, 0.6) 0.39 BMI, kg/m2 −0.2 (−0.9, 0.4) 0.49
Smoking status, never ref Smoking status, never ref
Smoking status, former −0.4 (−13.7, 14.8) 0.95 Smoking status, former 0.7 (−14.8, 18.9) 0.93
Smoking status, current −9.9 (−26.9, 11.2) 0.31 Smoking status, current −1.8 (−16.3, 15.2) 0.81
Age at menarche, years 0.2 (−2.0, 2.6) 0.82 Age at menarche, years 0.9 (−2.0, 4.0) 0.51
Breastfeeding −4.1 (−14.1, 7.0) 0.43 Breastfeeding 3.6 (−7.3, 15.8) 0.51
Tubal ligation 11.8 (−0.6, 25.7) 0.06 Tubal ligation −6.0 (−18.9, 8.9) 0.38
HT use, never ref HT use, never ref
HT use, former −10.2 (−20.2, 1.1) 0.07 HT use, former 7.0 (−7.5, 23.7) 0.34
HT use, current −7.8 (−17.5, 3.1) 0.14 HT use, current −4.2 (−17.6, 11.4) 0.56
Previous history of cancer 7.4 (−6.9, 23.9) 0.3 Previous history of cancer 9.2 (−8.8, 30.9) 0.31
Age at natural menopause, years Age at natural menopause, years
 <46 ref  <46 ref
 46–49 4.6 (−16.9, 31.8) 0.68  46–49 −16.9 (−33.8, 4.2) 0.10
 50–52 13.5 (−7.6, 39.5) 0.21  50–52 −9.2 (−30.8, 19.1) 0.46
 52≤ 11.9 (−9.5,38.4) 0.28  52≤ −24.0 (−36.5, −9.2) 0.005
 Missinga −0.2 (−18.3, 21.9) 0.98  Missinga −15.1 (−29.0, 1.6) 0.07
a

96% had surgical menopause