Table 2.
Multivariable adjusted associations between race/ethnicity and circulating biomarkers of CA125 and CA15.3, NHANES 2001–2002.
Predictors | Average % differences (95%CI) | p-value | Predictors | Average % Differences (95%CI) | p-value | |
---|---|---|---|---|---|---|
Non-Hispanic white | ref | Non-Hispanic white | ref | |||
Non-Hispanic black | −29.0 (−42.5, −12.2) | 0.004 | Non-Hispanic Black | 17.3 (−0.5, 38.3) | 0.06 | |
Mexican American | −6.4 (−18.1, 6.9) | 0.3 | Mexican American | 1.3 (−19.0, 26.7) | 0.9 | |
Age, years | 0.7 (0.2, 1.2) | 0.006 | Age, years | −0.2 (−1.0, 0.5) | 0.42 | |
BMI, kg/m2 | 0.4 (−1.4, 0.6) | 0.39 | BMI, kg/m2 | −0.2 (−0.9, 0.4) | 0.49 | |
Smoking status, never | ref | Smoking status, never | ref | |||
Smoking status, former | −0.4 (−13.7, 14.8) | 0.95 | Smoking status, former | 0.7 (−14.8, 18.9) | 0.93 | |
Smoking status, current | −9.9 (−26.9, 11.2) | 0.31 | Smoking status, current | −1.8 (−16.3, 15.2) | 0.81 | |
Age at menarche, years | 0.2 (−2.0, 2.6) | 0.82 | Age at menarche, years | 0.9 (−2.0, 4.0) | 0.51 | |
Breastfeeding | −4.1 (−14.1, 7.0) | 0.43 | Breastfeeding | 3.6 (−7.3, 15.8) | 0.51 | |
Tubal ligation | 11.8 (−0.6, 25.7) | 0.06 | Tubal ligation | −6.0 (−18.9, 8.9) | 0.38 | |
HT use, never | ref | HT use, never | ref | |||
HT use, former | −10.2 (−20.2, 1.1) | 0.07 | HT use, former | 7.0 (−7.5, 23.7) | 0.34 | |
HT use, current | −7.8 (−17.5, 3.1) | 0.14 | HT use, current | −4.2 (−17.6, 11.4) | 0.56 | |
Previous history of cancer | 7.4 (−6.9, 23.9) | 0.3 | Previous history of cancer | 9.2 (−8.8, 30.9) | 0.31 | |
Age at natural menopause, years | Age at natural menopause, years | |||||
<46 | ref | <46 | ref | |||
46–49 | 4.6 (−16.9, 31.8) | 0.68 | 46–49 | −16.9 (−33.8, 4.2) | 0.10 | |
50–52 | 13.5 (−7.6, 39.5) | 0.21 | 50–52 | −9.2 (−30.8, 19.1) | 0.46 | |
52≤ | 11.9 (−9.5,38.4) | 0.28 | 52≤ | −24.0 (−36.5, −9.2) | 0.005 | |
Missinga | −0.2 (−18.3, 21.9) | 0.98 | Missinga | −15.1 (−29.0, 1.6) | 0.07 |
96% had surgical menopause