. 2021 Feb 17;14(2):253–269. doi: 10.1007/s12304-021-09403-5

Table 4.

Top-ranked nucleotide sequences in the genomes of the human coronaviruses

	MERS		SARS		SARS-CoV-2		HCoV-229E		HCoV-HKU1		HCoV-NL63		HCoV-OC43
r	“word”	f_r	“word”	f_r	“word”	f_r	“word”	f_r	“word”	f_r	“word”	f_r	“word”	f_r
1	X	3098	X	2845	X	3215	X	3380	X	4694	X	4272	X	3895
2	G	876	G	795	G	858	G	1033	A	1183	G	1149	G	1105
3	A	701	C	568	A	623	A	615	G	1151	A	814	A	963
4	C	668	A	567	C	542	C	458	C	581	C	521	C	468
5	GC	256	GC	316	GC	255	GG	288	AA	399	GG	387	AA	324
6	GG	234	GA	217	GG	245	GC	284	GA	339	AA	318	GA	322
7	GA	223	GG	202	AA	218	AA	211	GG	338	GA	296	GG	293
8	AA	214	AC	196	AC	214	GA	210	AC	271	GC	232	GC	269
9	AC	194	AA	167	GA	208	AC	156	AG	227	AG	194	AC	190
10	AG	134	CA	154	AG	138	AG	128	GC	223	AC	190	AG	171
11	CC	131	AG	102	CA	127	CA	105	AAA	117	CA	107	CA	96
12	CA	126	CC	81	CC	79	CC	56	CA	113	CC	69	CC	86
13	CG	80	CG	74	AAA	64	GAC	52	CC	104	CG	58	AAA	76