Table 1.
Summary of the Timing and Vaccine Used in the Routine Immunization (RI) schedule and for Supplementary Immunization Activities (SIAs) in Israel
| Vaccination input | Best estimate | Source | Notes |
|---|---|---|---|
| Relative RI coverage in non-Jewish subpopulations between 1958–1993 | |||
| - Before 1979 | 0.30 | ||
| - 1979 | 0.40 | ||
| - 1980 | 0.50 | ||
| - 1981 | 0.60 | ||
| - 1982–1988 | 0.70 | ||
| - 1989–1990 | 0.80 | ||
| - 1991–1992 | 0.90 | ||
| - After 1993 | 1.00 | ||
| Relative SIA coverage in non-Jewish subpopulations | |||
| - Before 1979 | 0.40 | ||
| - 1979 | 0.50 | ||
| - 1980 | 0.60 | ||
| - 1981 | 0.70 | ||
| - 1982–1984 | 0.80 | ||
| - 2013 | 1.00 | ||
| Characterization of Salk IPV SIAs during 1957–1958 | [3] | ||
| - First day of first SIA, 1957 | 15 (Jan 15) | Children aged 6 months–2 years | |
| - First day of second SIA, 1957 | 46 (Feb 15) | Children aged 6 months–2 years | |
| - First day of third SIA, 1957 | 74 (March 15) | Children aged 3–29 years | |
| - First day of fourth SIA, 1957 | 105 (April 15) | Children aged 3 years | |
| - First day of fifth SIA, 1957 | 135(May 15) | Children aged 4–5 months | |
| - First day of sixth SIA, 1957 | 166 (June 15) | Children aged 4–5 months | |
| - First day of seventh SIA, 1958 | 15 (Jan 15) | Children aged 2–4 years | |
| - Duration of SIAs (days) | 14 | ||
| - True coverage in Jewish subpopulations | 0.93 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of IPV RI during 1958-1961 | [3] | The first 2 doses at 4 and 6 months of age. | |
| - Primary doses by age 6 months | 2 | ||
| - Primary doses at age 12 months | 1 | ||
| - Coverage in Jewish subpopulations | Time series | ||
| Characterization of mOPV1 SIAs during 1961-1962 | [4,5] | Children younger than 5 years | |
| - First day of first SIA, 1961 | 166 (June 15) | ||
| - First day of second SIA, 1962 | 32 (Feb 1) | ||
| - First day of third SIA, 1962 | 91 (April 1) | ||
| - Duration of SIAs (days) | 14 | ||
| - True coverage in Jewish subpopulations | 0.70 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of mOPV2 SIA in 1961 | [4,5] | Children younger than 5 years | |
| - First day of SIA | 319 (Nov 15) | ||
| - Duration of SIA (days) | 14 | ||
| - True coverage in Jewish subpopulations | 0.70 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of mOPV3 SIA in 1962 | [4,5] | Children younger than 5 years | |
| - First day of SIA | 152 (June 1) | ||
| - Duration of SIA (days) | 14 | ||
| - True coverage in Jewish subpopulations | 0.75 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of tOPV SIA in 1963 | [4,5] | Children younger than 5 years | |
| - First day of SIA | 32 (Feb 1) | ||
| - Duration of SIA (days) | 14 | ||
| - True coverage in Jewish subpopulations | 0.80 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of OPV RI during 1963–1988 | [4, 19] | The first 3 doses at 2, 4 and 6 months of age except Hadera between1982–1988 | |
| - Primary doses by age 6 months | 3 | ||
| - Primary doses at age 12 months | 1 | ||
| - Coverage in Jewish subpopulations | Time series | ||
| Characterization of IPV RI during 1982–1988 | [6,7, 20] | The first 2 doses at 2 and 4 months of age. Only in Hadera | |
| - Primary doses by age 6 months | 2 | ||
| - Primary doses at age 12 months | 1 | ||
| - Coverage in Jewish subpopulations | Time series | ||
| Characterization of mOPV1 SIAs during 1979–1982 | [4, 6] | Children younger than 3 years, mostly non-Jewish living in poor sanitary conditions with adjacent Jewish settlements | |
| - Frequency | Annual | ||
| - First day of SIA | 140 (May 25) | ||
| - Duration of SIA (days) | 14 | ||
| - True coverage in Jewish subpopulations | 0.80 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of mOPV1 SIAs during 1982–1984 | [6] | Only in Hadera among non-Jewish kids aged 0–2 years and born before 1982 | |
| - Frequency | Annual | ||
| - First day of SIA | 140 (May 25) | ||
| - Duration of SIA (days) | 14 | ||
| - True coverage in Jewish subpopulations | 1.00 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of tOPV outbreak response in 1988 in Hadera subpopulations | [6] | All people aged 2 months–29 years | |
| - First day of response (2013) | 263 (Sept 20) | ||
| - Duration of response (days) | 10 | ||
| - True coverage in Jewish subpopulations | 0.80 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of tOPV outbreak response in 1988 in Non-Hadera subpopulations | [6] | All people aged 2 months–29 years | |
| - First day of response (2013) | 283 (Oct 10) | ||
| - Duration of response (days) | 18 | ||
| - True coverage in Jewish subpopulations | 0.80 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of IPV/OPV RI during 1989–2004 | [7, 19] | At 2 months IPV. | |
| - Primary doses by age 6 months | 4 | At 4 months tOPV+IPV | |
| - Primary doses at age 12 months | 2 | At 6 months tOPV. | |
| - Booster doses at age 5 years | 1 | At 12 months tOPV+IPV. | |
| - Booster doses at age 15 years | 1 | Booster doses tOPV | |
| - Coverage | Time series | ||
| Characterization of IPV RI during 2005–2013 | [7, 19] | The firs3 doses at 2, 4 and 6 months | |
| - Primary doses by age 6 months | 3 | ||
| - Primary doses at age 12 months | 1 | ||
| - Booster doses at age 10 years | 1 | ||
| - Coverage | Time series | ||
| Characterization of IPV catch up before bOPV response to WPV1 circulation in 2013 in South districts | [10,11] | All children younger than 10 years who have not received any IPV doses in the past | |
| - First day of response (2013) | 186 (July 5) | ||
| - Duration of response (days) | 30 | ||
| - True coverage in Jewish subpopulations | 0.65 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of IPV booster dose before bOPV response to WPV1 circulation in 2013 in South districts | [10,11] | Adults who have not received any IPV doses in the past | |
| - First day of response (2013) | 186 (July 5) | ||
| - Duration of response (days) | 30 | ||
| - True coverage in Jewish subpopulations | 0.10 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of IPV catch up before bOPV response to WPV1 circulation in 2013 in non-South districts | [10,11] | All children younger than 10 years who have not received any IPV doses in the past | |
| - First day of response (2013) | 199 (July 18) | ||
| - Duration of response (days) | 30 | ||
| - True coverage in Jewish subpopulations | 0.65 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of bOPV response SIA to WPV1 circulation in 2013 in South district | [10,11] | All children born after 1 January 2004, who have received at least 1 dose of IPV in the past | |
| - First day of response (2013) | 217 (Aug 5) | ||
| - Duration of response (days) | 50 | ||
| - True coverage in Jewish subpopulations | 0.80 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of bOPV response SIA to WPV1 circulation in 2013 in non-South districts | [10,11] | All children born after 1 January 2004, who have received at least 1 dose of IPV in the past | |
| - First day of response (2013) | 230 (Aug 18) | ||
| - Duration of response (days) | 50 | ||
| - True coverage in Jewish subpopulations | 0.60 | ||
| - Repeated missed probability | 0.80 | ||
| Characterization of IPV RI between 2005–2013 | [7, 19] | At age 2 and 4 months - IPV. | |
| - Primary doses by age 6 months | 4 | At age 6 months - IPV+bOPV | |
| - Primary doses at age 12 months | 1 | At age 12 months - IPV | |
| - Primary doses at age 24 months | 1 | At age 24 months – bOPV+ | |
| - Booster doses at age 10 years | 1 | Booster dose IPV | |
| - Coverage | Time series |
*
The formulation of IPV changed in 1982 to increase the potency of the vaccine
Abbreviations: bOPV, bivalent oral polio vaccine; IPV, inactivated polio vaccine; mOPV, monovalent OPV; mOPV1, 2, and 3, monovalent OPV types 1, 2, and 3; RI, routine immunization; SIA, supplemental immunization activity; tOPV, trivalent OPV; WPV1, wild poliovirus type 1