Table 2.
Correlations between BMI changes and delta of gene expression in adipose tissue at 3 and 6 months after RYGB
| Correlation statistics | Correlation statistics | ||||
|---|---|---|---|---|---|
| Pearson’s r | p value | Pearson’s r | p value | ||
| 3 months | 6 months | ||||
| IL6 | 0.362 | 0.548 | IL6 | -0.305 | 0.5046 |
| TNFα | 0.344 | 0.570 | TNFα | -0.555 | 0.1954 |
| MCP1 | 0.497 | 0.394 | MCP1 | 0.183 | 0.6942 |
| ADIPOQ | -0.066 | 0.915 | ADIPOQ | 0.950 | 0.0010 |
| PGC1α | 0.961 | 0.009 | PGC1α | 0.386 | 0.3915 |
| PPARγ | 0.384 | 0.523 | PPARγ | 0.591 | 0.1623 |
| EIF2AK3 | 0.511 | 0.379 | EIF2AK3 | 0.165 | 0.7233 |
| ATF4 | 0.648 | 0.237 | ATF4 | -0.373 | 0.4097 |
| ATF6 | 0.410 | 0.492 | ATF6 | 0.677 | 0.0945 |
| CHOP | 0.254 | 0.680 | CHOP | -0.286 | 0.5332 |
| GRP78 | 0.261 | 0.671 | GRP78 | 0.46 | 0.2987 |
| GADD34 | -0.554 | 0.332 | GADD34 | -0.05 | 0.9141 |
| XBP1 | -0.609 | 0.275 | XBP1 | 0.232 | 0.6164 |
| CALR | 0.004 | 0.994 | CALR | 0.416 | 0.3523 |
| CANX | 0.490 | 0.401 | CANX | 0.743 | 0.0554 |
| CCT4 | 0.637 | 0.247 | CCT4 | 0.272 | 0.5539 |
| SIRT1 | 0.958 | 0.010 | SIRT1 | 0.844 | 0.0169 |
| SIRT3 | 0.407 | 0.496 | SIRT3 | 0.489 | 0.2646 |
| AMPK | 0.947 | 0.015 | AMPK | 0.692 | 0.0846 |
| GCN2 | -0.511 | 0.379 | GCN2 | 0.278 | 0.5459 |
| NRF2 | 0.127 | 0.839 | NRF2 | -0.014 | 0.9757 |
| SOD1 | -0.342 | 0.573 | SOD1 | -0.527 | 0.2232 |
| SOD2 | -0.710 | 0.178 | SOD2 | -0.112 | 0.8102 |
| SOD3 | -0.466 | 0.428 | SOD3 | 0.105 | 0.8227 |
IL6: Interleukin 6; TNF-ɑ: Tumor necrosis factor-α; MCP-1: Monocyte chemoattractant protein-1; PGC1ɑ: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PPARϒ: Peroxisome proliferator activated receptor gamma; EIF2AK3: Eukaryotic translation initiation factor 2 alpha kinase 3; ATF4: Activating Transcription Factor 4; ATF6: Activating Transcription Factor 6; CHOP: C/EBP homologous protein; GRP78: Heat shock protein family A (Hsp70) member 5; GADD34: growth arrest and DNA damage-inducible protein; XBP1: X-box binding protein 1; CARL: Calreticulin; CANX: Calnexin; CCT4: Chaperonin Containing TCP1 Subunit 4; SIRT1: Sirtuin 1; SIRT3: Sirtuin 3; AMPK: AMP-activated protein kinase; GCN2: General control nonderepressible 2; NRF2: Nuclear factor erythroid 2-related factor 2; SOD1: Superoxide dismutase 1; SOD2: Superoxide dismutase 2, SOD3: Superoxide dismutase 3