Table 2. Overview of the Data Sets Used for In Silico Model Development.
| number
of |
||||
|---|---|---|---|---|
| target abbreviation | assay name | active compounds | inactive compounds | ratio |
| DIO1 | NHEERL_MED_hDIO1_dn | 109 | 1610 | 1:15 |
| DIO2 | DIO2 inhibition | 178 | 1551 | 1:9 |
| DIO3 | DIO3 inhibition | 183 | 1545 | 1:8 |
| TPO | NCCT_TPO_AUR_dn | 256 | 796 | 1:3 |
| TR | TOX21_TR_LUC_GH3_Antagonist | 1251 | 5091 | 1:4 |
| NIS | NIS_RAIU_inhibition | 55 | 747 | 1:14 |
| TRHR | TOX21_TRHR_HEK293_Antagonist | 70 | 6548 | 1:94 |
| TSHRAnt | TOX21_TSHR_Antagonist_ratio | 116 | 6591 | 1:57 |
| TSHRAg | TOX21_TSHR_Agonist_ratio | 202 | 6587 | 1:33 |