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. 2020 Nov 13;34(2):396–411. doi: 10.1021/acs.chemrestox.0c00304

Table 3. Number of Compounds for Each Class at Different Steps in the Data Processing Workflow.

  number of compounds
  raw data
after filtering of compounds with any ToxCast flag
processed data sets used for model development
end point active inactive active inactive active inactive
DIO1 136 1683 119 1683 109 1610
DIO2 194 1625 a a 178 1551
DIO3 194 1625 a a 183 1545
TPO 489 830 264 810 256 796
TR 2376 5929 1354 5574 1251 5091
NIS 282 756 55 756 55 747
TRHR 317 7554 81 7161 70 6548
TSHRAnt 336 7535 116 7206 116 6591
TSHRAg 489 7382 222 7192 202 6587
a

Data not in the ToxCast database - no flag filtering step.