Table 8. Percentage of Compounds in the Reference Data Sets Covered by a Compound in the End-Point-Specific Data Sets at the Given Tanimoto Similarity Thresholds.

		end point
	Tanimoto similarity	DIO1	DIO2	DIO3	TPO	TR	NIS	TRHR	TSHRAnt	TSHRAg
% coverage pesticides	1.0.	57	57	57	47	56	35	65	65	70
	≥0.8	58	58	58	48	57	36	66	65	71
	≥0.6	67	68	68	58	68	47	76	76	79
	≥0.4	84	84	84	78	85	68	87	89	90
	≥0.2	99	99	99	98	99	98	99	99	99
% coverage cosmetics	1.0	16	16	16	9	37	7	39	40	39
	≥0.8	20	20	20	11	41	9	43	44	43
	≥0.6	34	34	34	19	58	17	59	60	59
	≥0.4	69	70	70	52	98	49	86	86	86
	≥0.2	95	95	95	92	98	92	98	98	98
% coverage drugs	1.0	5	5	5	3	22	2	20	20	20
	≥0.8	5	5	5	3	24	3	22	22	22
	≥0.6	10	10	10	7	37	6	33	34	33
	≥0.4	28	29	29	22	62	20	60	60	60
	≥0.2	95	95	95	93	98	91	98	98	98