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. 2021 Feb 16;19:77. doi: 10.1186/s12967-020-02694-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — ERp44 was highly expressed in NPC. a Western blot analysis was performed to reveal ERp44 expression in tissues. Tumor: Nasopharyngeal squamous cell carcinoma tissues. Normal: Inflammatory nasopharyngeal epithelium tissues. ACTB was used as a control. The bar demonstrated the expression of ERp44 relative to ACTB by densitometry. b qRT-PCR was used to detect ERp44 expression in NPC tissues and inflammatory nasopharyngeal tissues. c Representative results of immunohistochemical staining. Left: Inflammatory nasopharyngeal epithelium tissues had lower expression of ERp44 (up: × 20) (down: × 40). Middle and Right Line: NPC tissues had higher expression of ERp44 (up: × 20) (down: × 40). d Western blot was used to detect ERp44 expression in NPC cell lines CNE1, CNE2, 5-8F, 6-10B and normal nasopharyngeal epithelial cell NP69. Data represent mean ± SEM. *p < 0.05