Table 4. Measured 1-Octanol/PBS Partition Coefficients and log P Values of [18F]FAU, [18F]FMAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU, and [18F]FIAU.
radiotracer | partition coefficients of 1-octanol/PBSa | log P |
---|---|---|
[18F]FAU | 0.114 ± 0.011 | –0.943 ± 0.041 |
[18F]FMAU | 0.265 ± 0.002 | –0.577 ± 0.003 |
[18F]FEAU | 0.837 ± 0.035 | –0.077 ± 0.018 |
[18F]FFAU | 0.113 ± 0.006 | –0.952 ± 0.023 |
[18F]FCAU | 0.334 ± 0.022 | –0.477 ± 0.030 |
[18F]FBAU | 0.430 ± 0.024 | –0.367 ± 0.025 |
[18F]FIAU | 0.780 ± 0.024 | –0.108 ± 0.013 |
Measurements were carried out in quintuplicate for each tracer.