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. 2021 Jan 26;4(1):344–351. doi: 10.1021/acsptsci.0c00206

Figure 1.

Figure 1

In vitro evaluation of [211At]MM4 cytotoxicity in human glioblastoma (GBM) cell lines (experiments were performed in triplicate for each concentration and repeated three times). (A) Dose–response curves for each cell line or isogenic cell line pair treated with [211At]MM4 or free astatine-211. (B) Bar graph of effective concentrations for 50% reduction in cell survival (EC50) of treated GBM cell lines. (C) PARP1 mRNA expression in (GBM) cell lines obtained from the Cancer Cell Encyclopedia (https://portals.broadinstitute.org/ccle/about#contact) ([211At]NaAt: [211At] sodium astatide).