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. 2019 Dec 30;27(1):69–82. doi: 10.1080/26410397.2019.1691897

Table 4. Treatment recommendations for pregnant women, by World Health Organization (WHO) region (n = 128 countries).

  African Region (n = 22) Americas Region (n = 26) Eastern Mediterranean Region (n = 2) European Region (n = 53) South East Asian Region (n = 5) Western Pacific Region (n = 20)
Treatment recommended according to WHO guidelines n (%) n (%) n (%) n (%) n (%) n (%)
Early syphilis* BPG 2.4 MUIM single dose 20 (95%) 20 (78%) 2 (100%) 52 (98%) 5 (100%) 18 (90%)
Late latent syphilis BPG 7.2 MU IM in three weekly doses 16 (73%) 20 (77%) 1 (50%) 52 (98%) 5 (100%) 18 (90%)
BPG 7.2 MU IM in three weekly doses regardless of stage 2 (9%) 6 (23%) 0 0 0 0
Non-penicillin regimens were included as alternatives 20 (91%) 8 (31%) 2 (100%) 4 (8%) 5 (100%) 17 (85%)
Desensitisation recommended for penicillin allergic women 4 (18%) 19 (73%) 0 (0%) 53 (100%) 1 (20%) 16 (80%)

*Regarding early syphilis (primary, secondary and early latent syphilis).

†BPG = benzathine penicillin G.