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. 2021 Feb 17;21:105. doi: 10.1186/s12888-021-03097-2

Table 2.

Characteristics of the included studies and their population

Article Country Follow-up Sample size Demographics (mean age, gender, ethnicity) Inclusion criteria Exclusion criteria
Nilsson et al., 2019 [35] Sweden 12 months 136

35.6 years

81.6% males

Scoring ≥5 in PGSI, live in Sweden, understand and write Swedish and be aged at least 18 years. Severe psychiatric disorders.
Penna et al., 2018 [28] Brazil 8 weeks 59

54.03 years

57.6% males

78% caucasians

Diagnostic according DSM-5 criteria, ability to understand the purpose of the study, physically able to engage in physical activity, for female patients a negative pregnancy test. Severe psychiatric disorder or other medical condition requiring inpatient treatment.
Casey et al., 2017 [25] Australia 12 months 174

44.37 years

40.98% males

79.62% caucasians

Diagnostic according DSM-5 criteria, over 18 years of age, reside in Australia Receiving additional treatments, involved in legal proceedings, not proficient with English, at a high risk of suicide; were acutely psychotic, or if their gambling behaviour only occurred during manic episodes.
Bouchard et al., 2017 [20] Canada 2 weeks 25

47 years

50% males

Diagnostic according DSM-5 criteria and be treated at Centre CASA or Maison Jean-Lapointe in Canada
Smith et al., 2015 [47] Australia 9 months 99

46.49 years

49.43% males

Scoring ≥8 in SOGS, 18 years of age or older, gambling with electronic gaming machines, gambled in the past month Being suicidal, exhibiting acute psychosis or mania or experiencing significant mental distress, psychological treatment for problem gambling in the previous 12 months
Lee et al., 2014 [18] Canada 2 months 16

49.1 years

66% males

73% caucasians

One or both spouses diagnosed according DSM-IV criteria, gambled in the past 2 months, be at least 18 years of age and committed couple relationship Suicidal ideation, attempt at suicide or psychotic symptoms for the past month, recurring intimate partner violence or receiving additional treatments
Grant et al., 2011 [38] United States 6 months 68

49.01 years

66% males

94.12% caucasians

Diagnostic according DSM-IV criteria and gambled at least 1 time per week for the past 2 months Past 3-month substance use disorder, positive urine drug screen, current pharmacotherapy or psychotherapy for GD, previous GA attendance, any clinically significant suicidal ideation or current use of psychotropic medications
Myrseth et al., 2011 [31] Norway 6 months 30

32.8 years

86.67% males

Diagnostic according DSM-IV, minimum age of 18 years, not having used SSRIs for the last 6 months Suffering from epilepsy or liver/kidney disorders, evidence of psychosis or mental disorders, alcohol or drug dependency
Marceaux et al., 2010 [48] United States 6 months 49

46.57 years

34.69% males

85.71% caucasians

Diagnostic according DSM-IV and at least 21 years of age
Grant et al., 2009 [39] United States 8 weeks 68

48.7 years

36.8% males

Diagnostic according DSM-IV and had gambled at least once per week for the past 2 months Past 3-month substance use disorder, positive urine drug screen at screening, current psychotherapy or medication for GD, previous GA attendance or suicidal intentions
Myrseth et al., 2009 [29] Canada 3 months 14

37.43 years

78.57% males

Diagnostic according DSM-IV, ≥5 in SOGS and over 18 years of age Suffer from any type of substance abuse or from any psychotic disorder
Carlbring et al., 2009 [36] Sweden 12 months 150

40.5 years

83.5% males

Scoring ≥5 on NODS, speak Swedish and ability to complete self-report questionnaires Suicidal ideation, unwillingness to be randomized, medication for anxiety and/or depression, drug and/or alcohol dependence, or major mental disorders
Cunningham et al., 2009 [21] Canada 3 months 49

44.41 years

48.11% males

Diagnostic according DSM-IV criteria and interested in participating in the study
Carlbring et al., 2008 [37] Sweden 36 months 66

31.9 years

94% males

Scoring ≥5 on NODS, at least 18 years of age, live in Sweden and have gambled at least once in the past 30 days Having > 21 on MADRS depression scale, > 4 on the suicide item or playing computer games without betting money
Dowling et al., 2007 [16] Australia 6 months 56

43.58 years

100% females

Diagnostic according DSM-IV criteria
Petry et al., 2006 [41] United States 12 months 231

44.87 years

54.98% males

84.42% caucasians

Diagnostic according DSM-IV criteria, gambled in the past 2 months, were 18 years or older, and ability to read Current suicidal intentions, past-month psychotic symptoms, or already receiving gambling treatment
Melville et al., 2004 [14] United States 6 months 19

52.58 years

15.79% males

89% caucasians

Diagnostic according DSM-IV criteria and SOGS
Ladouceur et al., 2003 [49] Canada 24 months 71

43.41 years

77.97% males

Diagnostic according DSM-IV and willingness to undergo randomization Evidence of current or past schizophrenia, bipolar disorder, or organic mental disorder
Ladouceur et al., 2001 [50] Canada 12 months 101

41.98 years

82.81% males

Diagnostic according DSM-IV and be willing to undergo randomization Evidence of immediate suicidal intent or current or past schizophrenia, bipolar disorder or organic mental disorder
Sylvain et al., 1997 [51] Canada 12 months 29

40.19 years

100% males

100% caucasians

Diagnostic according DSM-III criteria, seeking help for gambling problems and rate motivation to change ≥7 (0–10)
Echeburua et al., 1996 [6] Spain 12 months 64

35 years

44.44% males

Diagnostic according DSM-III criteria, ≥8 in SOGS and gamble primarily with slot machines Suffering from other psychopathological disorders
McConaghy et al., 1991 [52] Australia 2–9 years 120

42.53 years

90.83% males

Diagnostic according DSM-III criteria Untreated active psychosis

NODS National Opinion Research Center DSM Screen for Gambling Problems, SOGS South Oaks Gambling Screen, DSM Diagnostic and Statistical Manual of Mental Disorders, PGSI Problem Gambling Severity Index, MADRS The Montgomery-Asberg Depression Rating Scale, GD Gambling Disorder, GA Gamblers Anonymous, SSRIs Selective serotonin reuptake inhibitors