Table 3.
Subgroup of the relationship between obesity, overweight, and BMI and incidence of bladder cancer
| Stratification criteria | Overweight, RR (95% CI) | Obesity, RR (95% CI) | Per 5 kg/m2, RR (95% CI) | |
|---|---|---|---|---|
| Sex | Male | 1.09 (0.99, 1.2) | 1.1 (1.05, 1.16) | 1.05 (1, 1.1) |
| Female | 1.06 (0.99, 1.14) | 1.08 (1.02, 1.14) | 1.02 (0.96, 1.09) | |
| P value | 0.647 | 0.185 | 0.474 | |
| Age | Age < 50 | 1.04 (0.97, 1.13) | 1.08 (1.02, 1.14) | |
| Age ≥ 50 | 1.11 (1.03, 1.19) | 1.15 (1.1, 1.2) | ||
| P value | 0.224 | 0.081 | ||
| Study location | Asia | 1.04 (0.99, 1.09) | 1.02 (0.97, 1.08) | |
| North America | 1.12 (1.03, 1.22) | 1.13 (1.07, 1.19) | 1.06 (1, 1.12) | |
| Europe | 1.09 (0.98, 1.2) | 1.06 (1.01, 1.12) | 1.02 (0.98, 1.06) | |
| Asia versus North America (P value) | 0.136 | 0.008 | ||
| Asia versus Europe (P value) | 0.412 | 0.312 | ||
| North America versus Europe (P value) | 0.687 | 0.091 | 0.274 | |
| Measure | BMI measured | 1.1 (1, 1.2) | 1.09 (1.05, 1.13) | |
| BMI self-measured | 1.12 (1.04, 1.19) | 1.18 (1.1, 1.27) | ||
| P value | 0.755 | 0.054 | ||
| Duration | Duration of follow-up < 10 years | 1.07 (1.03, 1.11) | 1.1 (1.05, 1.16) | |
| duration of follow-up ≥ 10 years | 1.07 (0.98, 1.17) | 1.1 (1.04, 1.15) | ||
| P value | 1.000 | 1.000 | ||
| Physical | Physical activity | 1.11 (0.99, 1.24) | 1.2 (1.08, 1.33) | |
| No physical activity | 1.03 (1, 1.07) | 1.09 (1.04, 1.13) | ||
| P value | 0.212 | 0.093 | ||
| History | Family history of cancer | 1.15 (1.05, 1.26) | 1.15 (1.09, 1.2) | |
| No family history of cancer | 1.06 (1.01, 1.11) | 1.09 (1.06, 1.13) | ||
| P value | 0.120 | 0.069 | ||
| Smoking | Smoking | 1.07 (0.99, 1.16) | 1.1 (1.04, 1.15) | |
| No smoking | 1.1 (1.05, 1.15) | 1.11 (1.07, 1.15) | ||
| P value | 0.553 | 0.774 | ||
| Alcohol | Alcohol | 1.13 (1.04, 1.22) | 1.17 (1.06, 1.3) | |
| No alcohol | 1.06 (0.99, 1.14) | 1.09 (1.05, 1.13) | ||
| P value | 0.443 | 0.002 | ||