Skip to main content
. 2021 Feb;191(2):368–384. doi: 10.1016/j.ajpath.2020.10.015

Figure 7.

Figure 7.

RNA-sequencing analysis of control and RAD6B knockout M14 melanoma cells and normal HEMa-LP melanocytes. A: Venn diagram of differentially expressed genes (DEGs; 1% false discovery rate and fold change ≥2) and overlap in RAD6B knockout (KO) compared with control (Ctrl) M14 and HEMa-LP cells. B–D: Hierarchical cluster maps of 701, 710, and 1202 genes, respectively, differentially expressed in RAD6B KO cells compared with control M14 and HEMa-LP cells. E–G: Canonical pathways identified by Ingenuity Pathway Analysis of 701, 710, and 1202 DEGs, respectively. BER, base excision repair; NER, nucleotide excision repair.