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. 2021 Feb 10;41(6):1265–1273. doi: 10.1523/JNEUROSCI.2380-20.2020

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Copyright © 2021 Sun et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 2. — Human brain MOR availability and natural variation in daylength. A, Mean distribution of MOR availability in the subjects. B, Local seasonal distribution of daylength (day + civil twilight). C, The brain cluster sensitive to the seasonal daylength changes in quadratic polynomial regression model. p < 0.05, FDR corrected. D, [¹¹C]carfentanil BP_ND in the brain cluster as a function of daylength. Red line shows polynomial LS (least-squares) regression curve (y ∼ x + x²) predicting BP_ND, and shaded area shows 95% CI.