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. 2021 Feb 17;96(5):1262–1275. doi: 10.1016/j.mayocp.2021.02.008

Table 1.

Mortality Rates Among COVID-19 Patients: Randomized Clinical Trials and Matched Control Studiesa

Study Location Convalescent plasma
 Control
 Statistics
Survivor Nonsurvivor Mortality (%) Survivor Nonsurvivor Mortality (%) OR P 95% CI
Randomized clinical trials
 Avendano-Sola et al18 Spain 38 0 0 39 4 9 0.11 .15 0.01-2.19
 Rasheed et al17 Iraq 20 1 5 20 8 29 0.13 .06 0.01-1.09
 Gharbharan et al13 The Netherlands 37 6 14 32 11 26 0.47 .18 0.16-1.42
 AlQahtani et al26 Bahrain 19 1 5 18 2 10 0.47 .56 0.04-5.69
 Libster et al27 Argentina 78 2 3 76 4 5 0.49 .41 0.09-2.74
 Li et al12 China 43 8 16 38 12 24 0.59 .30 0.22-1.59
 Ray et al28 India 30 10 25 26 14 35 0.62 .33 0.24-1.63
 Simonovich et al29 Argentina 197 25 11 93 12 11 0.98 .96 0.47-2.04
 Agarwal et al30 India 201 34 14 198 31 14 1.08 .77 0.64-1.83
 Bajpai et al31 India 11 3 21 14 1 7 3.82 .27 0.35-41.96
Random effects model 674 90 12 554 99 15 0.76 .14 0.54-1.09
Random effects model excluding Agarwal et al 473 56 11 356 68 16 0.65 .04 0.43-0.98
Matched control studies
 Duan et al32 China 10 0 0 7 3 30 0.10 .15 0.01-2.28
 Perotti et al42 Italy 43 3 7 16 7 30 0.16 .01 0.04-0.69
 Omrani et al44 Qatar 39 1 3 35 5 13 0.18 .13 0.02-1.61
 Hegerova et al45 Washington 18 2 10 14 6 30 0.26 .13 0.05-1.49
 Salazar et al,33 Texas 146 6 4 235 34 13 0.28 .01 0.12-0.69
 Alsharidah et al46 Kuwait 111 24 18 143 90 39 0.34 <.001 0.21-0.57
 Zeng et al47 China 1 5 83 1 14 93 0.36 .50 0.02-6.85
 Donato et al48 New York 36 11 23 775 565 42 0.42 .01 0.21-0.83
 Salazar et al49 Argentina 647 221 25 1288 1010 44 0.44 <.001 0.37-0.52
 Liu et al50 New York 34 5 13 118 38 24 0.46 .13 0.17-1.25
 Xia et al34 China 135 3 2 1371 59 4 0.52 .27 0.16-1.67
 Abolghasemi et al16 Iran 98 17 15 56 18 24 0.54 .10 0.26-1.13
 AlShehry et al35 Saudi Arabia 30 10 25 78 46 37 0.57 .16 0.25-1.26
 Budhiraja et al36 India 248 85 26 241 120 33 0.69 .03 0.50-0.96
 ah Yoon et al37 New York 50 23 32 45 28 38 0.74 .39 0.37-1.46
 Rogers et al38 Rhode Island 56 8 13 149 28 16 0.76 .52 0.33-1.77
 Altuntas et al39 Turkey 669 219 25 642 246 28 0.85 .15 0.69-1.06
 Klapholz et al40 New Jersey 37 10 21 38 9 19 1.14 .80 0.42-3.13
 Klein et al41 Maryland 25 9 26 26 8 24 1.17 .78 0.39-3.51
 Moniuszko-Malinowska et al43 Poland 49 6 11 672 43 6 1.91 .16 0.78-4.72
Random effects model 2482 668 21 5950 2377 29 0.57 <.001 0.45-0.72
Overall random effects modelb 2955 724 20 6306 2445 28 0.58 <.001 0.47-0.71
a

OR, odds ratio.

b

Random effects model excludes trial by Agarwal et al.