Table 2.
Sensitivity and specificity for the outcomes across different score cut-offs.
| Score | Respiratory failure |
In-hospital mortality |
||
|---|---|---|---|---|
| Sensitivity (%) | Specificity (%) | Sensitivity (%) | Specificity (%) | |
| qSOFA | ||||
| ≥1a | 55.84 (44.1–67.2) | 81.87 (75.0–87.5) | 63.27 (48.3–76.6) | 78.19 (71.6–83.9) |
| ≥2 | 7.79 (2.9–16.2) | 98.12 (94.6–99.6) | 12.24 (4.6–24.8) | 98.4 (95.4–99.7) |
| ≥3 | 0 (0–4.7) | 100 (97.7–100) | 0 (0–7.3) | 100 (98.1–100) |
| SOFA | ||||
| ≥1 | 84.21 (74.0–91.6) | 44.38 (36.5–52.4) | 89.58 (77.3–96.5) | 41.49 (34.4–48.9) |
| ≥2a | 73.68 (62.3–83.1) | 69.37 (61.6–76.4) | 83.33 (69.8–92.5) | 65.43 (58.2–72.2) |
| ≥3 | 35.53 (24.9–47.3) | 87.5 (81.4–92.2) | 47.92 (33.3–62.8) | 87.23 (81.6–91.6) |
| ≥4 | 19.74 (11.5–30.5) | 96.25 (92.0–98.6) | 25 (13.6–39.6) | 95.21 (91.1–97.8) |
| ≥5 | 6.58 (2.2–14.7) | 98.12 (94.6–99.6) | 8.33 (2.3–20.0) | 97.87 (94.6–99.4) |
| ≥6 | 3.95 (0.8–11.1) | 99.37 (96.6–100) | 6.25 (1.3–17.2) | 98.94 (96.2–99.9) |
| ≥7 | 1.32 (0.03–7.1) | 100 (97.7–100) | 4.17 (0.5–14.3) | 100 (98.1–100) |
| qNEWS | ||||
| ≥1 | 63.64 (51.9–74.3) | 68.12 (60.3–75.3) | 65.31 (50.4–78.3) | 63.83 (56.5–70.7) |
| ≥2a | 61.04 (49.2–72.0) | 74.37 (66.9–80.9) | 65.31 (50.4–78.3) | 70.21 (63.1–76.6) |
| ≥3 | 44.16 (32.8–55.9) | 88.12 (82.1–92.7) | 42.86 (28.8–57.8) | 82.98 (76.8–88.1) |
| ≥4 | 7.79 (2.9–16.2) | 98.12 (94.6–99.6) | 8.16 (2.3–19.6) | 97.34 (93.9–99.1) |
| ≥5 | 3.9 (0.8–11.0) | 98.12 (94.6–99.6) | 6.12 (1.3–16.9) | 98.4 (95.4–99.7) |
| ≥6 | 2.6 (0.3–9.1) | 100 (97.7–100) | 65.31 (50.4–78.3) | 63.83 (56.5–70.7) |
| NEWS | ||||
| ≥1 | 92.2 (83.8–97.1) | 16.25 (10.9–22.9) | 91.84 (80.4–97.7) | 14.89 (10.1–20.8) |
| ≥2 | 87.0 (77.4–93.6) | 35 (27.6–42.9) | 87.76 (75.2–95.4) | 31.91 (25.3–39.1) |
| ≥3 | 83.12 (72.9–90.7) | 56.25 (48.2–64.1) | 83.67 (70.3–92.7) | 50.53 (43.2–57.9) |
| ≥4a | 71.43 (60.0–81.2) | 71.87 (64.2–78.7) | 77.55 (63.4–88.2) | 67.02 (59.8–73.7) |
| ≥5 | 54.55 (42.8–65.9) | 81.25 (74.3–87.0) | 55.1 (40.2–69.3) | 76.06 (69.3–82.0) |
| ≥6 | 45.45 (34.1–57.2) | 89.37 (83.5–93.7) | 44.9 (30.7–59.8) | 84.04 (78.0–89.0) |
| ≥7 | 35.06 (24.5–46.8) | 93.12 (88.0–96.5) | 34.69 (21.7–49.6) | 88.83 (83.4–93.0) |
| ≥8 | 24.68 (15.6–35.8) | 95.62 (91.2–98.2) | 24.49 (13.3–38.9) | 92.55 (87.8–95.9) |
| ≥9 | 11.69 (5.5–21.0) | 96.25 (92.0–98.6) | 12.24 (4.6–24.8) | 95.21 (91.1–97.8) |
| ≥10 | 3.9 (0.8–11.0) | 98.75 (95.6–99.8) | 4.08 (0.5–14.0) | 98.4 (95.4–99.7) |
Data are presented as percentages with 95% confidence intervals.
a
Best cut-off values for predicting respiratory failure and mortality.
qSOFA: Quick Sequential Organ Failure Assessment; SOFA: Sequential Organ Failure Assessment; NEWS: National Early Warning Score, qNEWS: quick National Early Warning Score.