Table 4.
Comparison of characteristics of participants with cardiotoxicity, between “others” and the main ethnic groups (Chinese, Malay, and Indian).
| Characteristics | Others (n = 9) | Main ethic groups (n = 23) | p-value |
|---|---|---|---|
| Demographic | |||
| Sex | 1.00 | ||
| Female | 3 (33.3) | 7 (30.4) | |
| Male | 6 (66.7) | 16 (69.6) | |
| Clinical | |||
| Diagnosis | |||
| Acute Lymphoblastic Leukemia (ALL) | 3 | 8 | |
| Acute Myeloid Leukemia (AML) | 3 | 5 | |
| Neuroblastoma | 0 | 5 | |
| Osteosarcoma | 1 | 3 | |
| Lymphoma | 1 | 1 | |
| Ewing Sarcoma | 1 | 0 | |
| Hepatoblastoma | 0 | 1 | |
| Age at diagnosis, years | 10.4 (3.9–12.5) | 6.9 (2.9–13.1) |
0.71 |
| Cumulative doxorubicin equivalent dose, mg/m2 | 300 (120–300) | 200 (150–360) |
0.86 |
| <250 mg/m2 | 4 (44.4) | 13 (56.5) | |
| ≥250 mg/m2 | 5 (55.6) | 10 (43.5) | 0.69 |
| Radiation involving the heart | 2 (22.2) | 1 (4.3) | 0.18 |