Table 4.

Multivariable logistic regression model with MDA at T6 as outcome and Cox regression model with time-to-SEC withdrawal as outcome

Independent variables	MDA at T6		Time to SEC withdrawal
	Multivariable analysis		Multivariable analysis
	OR (95% CI)	P value	HR (95% CI)	P value
Male sex	1.60 (1.05 to 2.45)	0.028	0.68 (0.48 to 0.97)	0.032
Age	0.99 (0.98 to 1.02)	0.892	1.01 (0.98 to 1.02)	0.704
Smoking	1.12 (0.70 to 1.80)	0.626	1.15 (0.78 to 1.69)	0.475
Psoriasis	1.31 (0.83 to 2.06)	0.240	1.07 (0.73 to 1.58)	0.720
Bio-naïve	0.93 (0.55 to 1.55)	0.786	1.20 (0.78 to 1.86)	0.397
Dosage SEC 300 mg	1.67 (0.41 to 1.11)	0.123	1.82 (0.36 to 0.84)	0.006
BMI	1.02 (0.97 to 1.06)	0.461	1.04 (1.01 to 1.07)	0.015
csDMARDs at T0	0.62 (0.41 to 0.95)	0.030	1.87 (1.18 to 2.80)	0.417
DAPSA at T0	0.94 (0.92 to 0.96)	0.010	1.00 (0.98 to 1.01)	0.638

P≤0.05.

The bold allows to highlight the values in which a statistical significance has been obtained.

Bio-naïve, first biological treatment line; BMI, body mass index; Coeff, coefficient; csDMARDs, conventional synthetic disease-modifying antirheumatic drugs; DAPSA, Disease Activity Index for Psoriatic Arthritis; MDA, minimal disease activity; SEC, secukinumab; T6, 6 months.