Table 1.
Demographic characteristics of patients with cancer presenting to the emergency department with sepsis
| Solid tumours (N=305) | Liquid tumours (N=137) | P value | ||
| Age (mean±SD) | (67.92±13.32) | (55.37±20.85) | <0.0001 | |
| Gender | Male, n (%) | 190 (62.3) | 97 (70.8) | 0.08 |
| Female, n (%) | 115 (37.7) | 40 (29.2) | ||
| Smoking, n (%) | 36 (14.6) | 16 (14.2) | 0.92 | |
| Medical history | Chronic kidney disease, n (%) | 40 (13.3) | 18 (13.2) | 0.98 |
| End-stage renal disease, n (%) | 7 (2.3) | 3 (2.2) | 1 | |
| Hypertension, n (%) | 156 (51.1) | 50 (36.5) | 0.004 | |
| Dyslipidaemia, n (%) | 62 (20.3) | 21 (15.3) | 0.21 | |
| Heart failure, n (%) | 86 (30.1) | 38 (30.2) | 0.99 | |
| Atrial fibrillation, n (%) | 34 (11.1) | 13 (9.5) | 0.6 | |
| Coronary artery disease, n (%) | 64 (21.0) | 19 (13.9) | 0.07 | |
| TIA or stroke, n (%) | 8 (2.6) | 3 (2.2) | 1 | |
| Vascular disease, n (%) | 13 (4.3) | 4 (2.9) | 0.49 | |
| Diabetes mellitus, n (%) | 99 (32.5) | 29 (21.2) | 0.02 | |
| COPD, n (%) | 29 (9.5) | 4 (2.9) | 0.06 | |
| Site of infection | Bone, n (%) | 0 (0.0) | 1 (0.8) | 0.31 |
| Peritoneum, n (%) | 4 (1.3) | 0 (0.0) | 0.32 | |
| Surgical site, n (%) | 4 (1.3) | 1 (0.8) | 1 | |
| Liver, n (%) | 4 (1.3) | 0 (0.0) | 0.32 | |
| Heart, n (%) | 4 (1.3) | 1 (0.8) | 1 | |
| Skin, n (%) | 8 (2.7) | 10 (7.5) | 0.02 | |
| Urine, n (%) | 66 (22.1) | 25 (18.7) | 0.41 | |
| Blood, n (%) | 57 (19.1) | 55 (41.4) | <0.0001 | |
| Gastrointestinal, n (%) | 60 (20.1) | 21 (15.8) | 0.29 | |
| Lung, n (%) | 131 (44.1) | 47 (35.6) | 0.09 | |
| Gallbladder, n (%) | 9 (3.0) | 0 (0.0) | 0.06 | |
| Other, n (%) | 7 (2.3) | 4 (3.0) | 0.74 | |
| Bacteria blood, n (%) | Klebsiella pneumonia, n (%) | 7 (2.3) | 1 (0.7) | 0.44 |
| Escherichia coli, n (%) | 50 (16.4) | 35 (25.5) | 0.02 | |
| Streptococcus species, n (%) | 12 (3.9) | 3 (2.2) | 0.41 | |
| Enterococcus species, n (%) | 7 (2.3) | 2 (1.5) | 0.73 | |
| Pseudomonas aeruginosa, n (%) | 9 (3.0) | 8 (5.8) | 0.14 | |
| Staphylococcus coagulase negative, n (%) | 27 (8.9) | 12 (8.8) | 0.97 | |
| Staphylococcus aureus, n (%) | 5 (1.6) | 3 (2.2) | 0.71 | |
| Proteus mirabilis, n (%) | 4 (1.3) | 0 (0.0) | 0.32 | |
| Acinetobacter baumani, n (%) | 2 (0.7) | 0 (0.0) | 1 | |
| Bacteria urine, n (%) | Klebsiella pneumonia, n (%) | 13 (4.3) | 1 (0.7) | 0.07 |
| E. coli, n (%) | 43 (14.1) | 16 (11.7) | 0.49 | |
| Enterococcus species, n (%) | 7 (2.3) | 1 (0.7) | 0.44 | |
| P. aeruginosa, n (%) | 4 (1.3) | 3 (2.2) | 0.68 | |
| S. aureus, n (%) | 1 (0.3) | 1 (0.7) | 0.52 | |
| P. mirabilis, n (%) | 1 (0.3) | 1 (0.7) | 0.52 | |
| A. baumani, n (%) | 3 (1.0) | 2 (1.5) | 0.65 | |
| On G-CSF, n (%) | 42 (13.8) | 53 (38.7) | <0.0001 |
COPD, Chronic obstructive pulmonary disease; G-CSF, granulocyte-colony stimulating factor; TIA, Transient ischemic attack.