Table 3.
Vital signs and laboratory workup of patients with cancer presenting to the emergency department with sepsis
| Solid tumours (N=305) | Liquid tumours (N=137) | P value | |
| Temperature (°C), (mean±SD) | (37.22±0.94) | (37.72±1.14) | <0.0001 |
| Temperature ≥38.5°C | 42 (14.3) | 37 (27.6) | 0.001 |
| Heart rate (beats/min), (mean±SD) | (109.29±23.25) | (111.53±25.12) | 0.01 |
| Heart rate ≥100 | 194 (64.0) | 102 (75.0) | 0.02 |
| Systolic blood pressure (SBP) (mm Hg), (mean±SD) | (110.39±26.45) | (114.56±22.43) | 0.09 |
| Diastolic blood pressure (mm Hg), (mean±SD) | (63.11±17.99) | (62.59±15.82) | 0.77 |
| Respiratory rate (breaths/min), (mean±SD) | (22.99±6.54) | (22.08±5.68) | 0.17 |
| Oxygen saturation (%), (mean±SD) | (93.50±8.45) | (95.52±6.76) | 0.02 |
| Oxygen saturation <90% | 58 (19.3) | 17 (12.9) | 0.11 |
| qSOFA criteria | |||
| Altered mental status | 80 (26.2) | 27 (19.7) | 0.14 |
| Respiratory rate >22 | 134 (43.9) | 65 (47.4) | 0.49 |
| SBP <100 | 127 (41.6) | 49 (35.8) | 0.24 |
| ≥2, n (%) | 108 (35.4) | 41 (29.9) | 0.26 |
| Lactate at presentation (mean±SD) | (3.81±2.82) | (3.72±3.28) | 0.8 |
| Albumin (mean±SD) | (25.59±6.06) | (29.45±7.35) | 0 |
| Glucose (mean±SD) | (147.47±71.03) | (143.65±67.27) | 0.66 |
| WCC (mean±SD) | (12.58±10.52) | (9.14.23±16. 48) | 0.03 |
| ANC (mean±SD) | (10.67 ±9.25) | (3.38±5.30) | <0.0001 |
| Haemoglobin (mean±SD) | (105.4±20.1) | (95.7±20.9) | <0.0001 |
| BUN (mean±SD) | (36.21±26.13) | (27.43±25.76) | <0.0001 |
| Creatinine (mean±SD) | (1.61±1.44) | (1.20±0.97) | <0.0001 |
| Baseline creatinine (mean±SD) | (2.08±0.92) | (2.03±1.00) | 0.86 |
| Sodium (mean±SD) | (134.15±6.26) | (135.92±5.25) | 0.002 |
| Bicarbonate (mean±SD) | (20.52±5.66) | (22.16±4.90) | 0.002 |
| Total bilirubin (mean±SD) | (2.91±5.45) | (0.83±0.67) | <0.0001 |
| Troponin (mean±SD) | (0.11±0.13) | (0.08±0.08) | 0.48 |
| INR (mean±SD) | (1.83±3.17) | (1.68±1.16) | 0.71 |
| pH arterial (mean±SD) | (7.35±0.91) | (7.39±0.08) | 0.03 |
Temperature in °C, heart rate in beats/minute, SBP and diastolic blood pressure in mm Hg, respiratory rate in breaths/minute, oxygen saturation in %, WCC in x109/L, ANC in x109/L, haemoglobin in g/L, haematocrit in %, BUN, creatinine, phosphate, calcium, magnesium, total bilirubin in mg/dL.
Sodium, potassium, bicarbonate, chloride in mmol/L, PT and PTT in seconds, PaCO2, PaO2/FiO2 in mm Hg.
ANC, absolute neutrophil count; BUN, blood urea nitrogen; INR, international normalised ratio; PaCO2, partial pressure of carbon dioxide; PaO2/FiO2, partial pressure of oxygen/ fraction of inspired oxygen; PT, prothrombin time; PTT, partial thromboplastin time; qSOFA, quick sepsis-related organ failure assessment; WCC, white cell count.