Table 4.
Sepsis treatment variables, LOS and outcomes of patients with cancer presenting to the ED with sepsis
| Solid tumours (N=305) | Liquid tumours (N=137) | P value | ||
| Intravenous fluid requirement (mean±SD) | First 6 hours (mean±SD) | (2.53±1.85) | (2.27±1.83) | 0.16 |
| First 24 hours (mean±SD) | (3.75±2.24) | (3.61±2.32) | 0.57 | |
| Vasopressor use in 24 hours | 90 (29.5) | 41 (29.9) | 0.91 | |
| Norepinephrine, n (%) | 87 (28.5) | 40 (29.2) | 0.88 | |
| Dopamine, n (%) | 5 (1.6) | 3 (2.2) | 0.71 | |
| Dobutamine, n (%) | 1 (0.3) | 2 (1.5) | 0.23 | |
| Epinephrine, n (%) | 8 (2.6) | 2 (1.5) | 0.73 | |
| Steroid use, n (%) | 66 (21.7) | 39 (28.5) | 0.11 | |
| Intubation in the first 24 hours | 47 (15.5) | 17 (12.5) | 0.41 | |
| Intubation within the first 48 hours | 31 (10.2) | 14 (10.3) | 0.97 | |
| ED LOS (mean±SD) | (17.77±23.77) | (15.99±28.17) | 0.49 | |
| ED Disposition: admitted to hospital, n (%) | 298 (97.7) | 137 (100.0) | 0.24 | |
| Admission disposition | ||||
| GPU | 146 (46.9) | 67 (49) | 0.004 | |
| ICU | 162 (53.1) | 70 (51) | 0.37 | |
| ICU LOS (mean±SD) | (212.04±370.81) | (181.79±267.40) | 0.57 | |
| GPU LOS (mean±SD) | (161.85±285.73) | (259.81±456.35) | 0.13 | |
| Total LOS (mean±SD) | (391.61±410.66) | (462.56±511.67) | 0.3 | |
| Hospital mortality | 158 (51.8) | 57 (41.6) | 0.05 | |
| Disposition | 0.09 | |||
| Discharged home, n (%) | 143 (46.9) | 79 (57.7) | ||
| Other, n (%) | 4 (1.0) | 1 (0.7) | ||
Intravenous fluid requirement in mL/kg, time to vasopressor use, time to initiation of antibiotics, ED LOS, ICU LOS, GPU LOS in hours.
ED, emergency department; GPU, general practitioner unit; ICU, intensive care unit; LOS, length of stay.