Table 2.
Top 10 up- and down- regulated genes in FLHS affected chickens
| Gene | log2(fold change) | p-value | Padj | Regulate |
|---|---|---|---|---|
| PLA2G5 | 7.03 | 6.89E-04 | 4.99E-02 | Up |
| DEGS2 | 5.91 | 1.48E-04 | 1.89E-02 | Up |
| RSPO4 | 5.17 | 6.13E-07 | 5.72E-04 | Up |
| GGCL1 | 4.50 | 1.14E-08 | 2.28E-05 | Up |
| IL6 | 4.36 | 5.55E-07 | 5.55E-04 | Up |
| SLC9A2 | 3.87 | 4.63E-04 | 3.92E-02 | Up |
| SLITRK4 | 3.65 | 7.88E-06 | 3.34E-03 | Up |
| ATP6V0D2 | 3.47 | 8.80E-06 | 3.62E-03 | Up |
| IL13RA2 | 3.18 | 5.75E-06 | 2.76E-03 | Up |
| EPHA1 | 3.16 | 5.74E-05 | 1.07E-02 | Up |
| WFIKKN2 | −2.73 | 1.54E-04 | 1.94E-02 | Down |
| RD3L | −1.91 | 1.33E-05 | 4.55E-03 | Down |
| PLIN3 | −1.87 | 5.62E-04 | 4.39E-02 | Down |
| PIANP | −1.58 | 4.64E-04 | 3.92E-02 | Down |
| PLPP1 | −1.49 | 9.44E-05 | 1.43E-02 | Down |
| RFESD | −1.48 | 8.31E-05 | 1.34E-02 | Down |
| TMEM26 | −1.40 | 3.03E-11 | 4.25E-07 | Down |
| LRRTM4 | −1.37 | 3.39E-04 | 3.24E-02 | Down |
| RASSF9 | −1.29 | 9.36E-05 | 1.43E-02 | Down |
PLA2G5, phospholipase A2 group V; DEGS2, delta 4-desaturase sphingolipid 2; RSPO4, R-Spondin 4; GGCL1, gallus chemokine-like ligand 1; IL6, interleukin-6; SLC9A2, solute carrier family 9 member 2; SLITRK4, slit and NTRK like family member 4; ATP6V0D2, ATPase H+ Transporting V0 subunit d2; IL13RA2, interleukin 13 receptor subunit alpha 2; EPHA1, eph receptor a1; WFIKKN2, WAP kunitz and netrin domain containing 2; RD3L, retinal degeneration 3 like; PLIN3, perilipin 3; PIANP, PILR alpha associated neural protein; PLPP1, phospholipid phosphatase 1; RFESD, RIESKE FE-S domain containing; TMEM26, transmembrane protein 26; LRRTM4, leucine rich repeat transmembrane neuronal 4; RASSF9, Ras association domain family member 9.