Fig 3. Decreased levels of PAICS expression was associated with poor survival in three independent cohorts.
(A-F) Kaplan-Meier curves for relapse-free survival according to the expression of PAICS transcript in stage II (A, C and E) and stage III (B, D and F) patients in the MSK cohort (A-B), the CIT cohort (C-D) and the Oslo cohort (E-F). In each cohort, patients were dichotomized based on PAICS levels into PAICS-Low with the lowest quartile and PAICS-High with the higher 3 quartiles.