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. 2021 Feb 17;16(2):e0247169. doi: 10.1371/journal.pone.0247169

Fig 5. Decreased expression of PAICS correlated with loss of chromosome arm 4q.

Fig 5

(A-B) Correlation between PAICS copy number and PAICS expression in the TCGA cohort (A) and the CCLE cohort (B). (C) Reduced levels of PAICS expression in tumors exhibiting loss of chromosome 4q in the TCGA cohort. (D) Increased occurrence of loss of chromosome 4q in advanced stage tumors in the TCGA cohort. (E-H) Decreased PAICS expression in MSI-L or MSS tumors compared to MSI-H tumors in the MSK cohort (E), the CIT cohort (F), the Oslo cohort (G) and the CCLE cohort (H). ****P<0.0001, ***P<0.001, **P<0.01, *P<0.05.