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. 2021 Feb 17;7(8):eabb6596. doi: 10.1126/sciadv.abb6596

Fig. 1. The expression and distribution of RLN receptor RXFP1 in desmoplastic tumors.

Fig. 1

(A) The distribution of RXFP1 in three different desmoplastic tumors including KPC pancreatic cancer, BPD6 melanoma, and 4T1 breast cancer (n = 5 samples per group). Macrophages were stained with anti-F4/80 in cyan, and fibroblasts in the tumor tissue were stained with anti–α-SMA (green). RXFP1 was stained in red with the anti-RXFP1 antibody. Cell nuclei were stained with DAPI in blue. (B) The distribution of RXFP1 in KPC pancreatic tumor further evaluated by flow cytometry (n = 6). Statistical significance was calculated using t test. *P < 0.05, ***P < 0.001.