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Functional and Molecular Features of Conventional TBC Types
| Cell Type | Type I | Type II | Type III |
|---|---|---|---|
| Function | Glial-like: | Transduction | Transduction |
| Ionic Homeostasis Neurotransmitter reuptake and degradation |
Sweet, Bitter or Umami T1Rs and T2Rs |
Sour Otop1 |
|
| Molecular Features | NTPDase2 ROMK GAD65 GLAST |
PLCβ2 TRPM5 CALHM1/3 IP3R3 Skn1a |
PGP9.5 PKD2L1 Car4 GAD67 Mash1 Serotonin |
| Synaptic Mechanism | none | Channel Synapses (CALHM1/3) | Vesicular Synapses (SNAP25) |
