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. 2021 Feb 9;13(1):1826746. doi: 10.1080/19490976.2020.1826746

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© 2021 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — B. adolescentis ATCC15703 gavage ameliorated the DSS induced chronic colitis

(a) Experimental animal model for chronic colitis. (b) Diarrhea score was recorded during the experiment according to rectal bleeding and diarrhea. (c) The entire colon was harvested on day 36. Colon length and colon inflammation were analyzed in the negative control mice and the PBS or B. adolescentis ATCC15703 gavage mice with DSS. (d) Representative pictures of H&E-stained (scale bars, 500 µm; blue arrows, inflammatory cells). (e) Cumulative scores including inflammation damage, inflammation infiltration and crypt damage were measured. (f) Spleen weight was measured. Data are expressed as mean ± SD, n = 6–9. *p < .05, **p < .01, ***p < .001 (ANOVA test). NC, negative control; DSS, dextran sulfate sodium; PBS, phosphate buffered saline; B.a, Bifidobacterium adolescentis.