Table 1.

Linkage analysis results between the Adipoq-Cre transgene and the Adam10 locus

	Genotypes
	Cre+; F/F	Cre+; F/W	Cre-; F/F	Cre-; F/W
Expected (%)	25	25	25	25
Actual (%)	2.2	47.3	47.3	2.2
n = 91	2	43	43	2
Thetaa:	0.044
Genetic Distance (cM):	4.4
LOD Score (Z)b,c:	25.6

^atheta = recombination frequency

^bLOD Score (Z) = log₁₀[[(theta^0)*((1-theta)^n)]/[((1/2)^0)*((1/2)^n)]]

^cLOD ≥ 3; definitive evidence two loci are linked