Table 3.
Seven ASVs that showed significant agreement* with regards to the probabilities of presence or absence (Kappa statistics) between saliva and any pancreatic tissue or intestinal samples
ASV IDb | Kappa (SD) | q-value | Agree obs | Prop.pp | Prop.pa | Prop.ap | Prop.aa | Genusa | Species (HOMD)a |
---|---|---|---|---|---|---|---|---|---|
ASV28 | 0.406 (0.116) | 0.004 | 0.896 | 0.042 | 0.104 | 0.000 | 0.854 | Fusobacterium | nucleatum subsp. vincentii |
ASV23 | 0.492 (0.137) | 0.004 | 0.896 | 0.063 | 0.083 | 0.021 | 0.833 | Rothia | mucilaginosa (GG) |
ASV20 | 0.431 (0.142) | 0.013 | 0.875 | 0.063 | 0.083 | 0.042 | 0.813 | Saccharibacteria_(TM7)_[G-1] | bacterium_HMT_352 |
ASV27 | 0.357 (0.111) | 0.009 | 0.875 | 0.042 | 0.125 | 0.000 | 0.833 | Oribacterium | parvum |
ASV01 | 0.344 (0.119) | 0.016 | 0.708 | 0.563 | 0.271 | 0.021 | 0.146 | Streptococcus | |
ASV47 | 0.309 (0.104) | 0.014 | 0.917 | 0.021 | 0.000 | 0.083 | 0.896 | Fusobacterium | nucleatum subsp. vincentii |
ASV17 | 0.284 (0.101) | 0.017 | 0.729 | 0.083 | 0.271 | 0.000 | 0.646 | Fusobacterium |
Agree obs = observed agreement; ASV = Amplicon Sequence Variants; SD = standard deviation; q-value = p-value adjusted for multiple testing via the false discovery rate method; Prop. pp = probability of an ASV to be present in both oral and any pancreatic tissue or intestinal samples; Prop. pa = probability of an ASV to be present in oral samples but absent in pancreatic or intestinal samples; Prop. ap = probability of an ASV to be absent in oral samples but present in pancreatic or intestinal samples; Prop. aa = probability of an ASV to be absent in both oral and any pancreatic tissue or intestinal samples.
*Significant agreement/concordance can be reached if probability of an ASV to be present in both oral and any pancreatic tissue or intestinal samples (Prop. pp), or probability of an ASV to be absent in both oral and any pancreatic tissue or intestinal sample (Prop. aa) is high.
aTAXONOMIC annotations of the ASVs are from HOMD database unless otherwise noted. GG = green gene database.
bSV ID used in Figure 1 left panel.