Table 3.
Cox proportional analysis of predictors associated with mortality in initially asymptomatic patients with COVID-19.
| Univariate |
Multivariate |
|||
|---|---|---|---|---|
| Hazard ratio (95% CI) | p Value | Hazard ratio (95% CI) | p Value | |
| Age ≥ 70 years | 30.98 (13.16–72.94) | <.001 | ||
| Male sex | 0.69 (0.38–1.22) | .20 | ||
| Body mass index < 18.5 kg/m2 | 2.56 (0.56–11.61) | .22 | ||
| Systolic blood pressure < 120 mmHg | 1.23 (0.63–2.39) | .54 | ||
| Diastolic blood pressure < 80 mmHg | 1.12 (0.62–2.03) | .71 | ||
| Heart rate ≥ 100/min | 1.13 (0.51–2.54) | .76 | ||
| CCIS 3–4 | 22.20 (2.73–180.44) | .004 | 6.58 (0.73–59.35) | .09 |
| ≥5 | 158.80 (21.82–1155.85) | <.001 | 61.91 (8.29–462.62) | <.001 |
| Diabetes | 4.54 (2.54–8.10) | <.001 | ||
| Hypertension | 4.99 (2.82–8.83) | <.001 | ||
| Congestive heart failure | 8.79 (3.47–22.27) | <.001 | ||
| Chronic heart disease | 6.64 (3.10–14.19) | <.001 | ||
| Asthma | 2.81 (0.68–11.58) | .15 | ||
| Chronic pulmonary obstructive disease | 19.71 (7.74–50.22) | <.001 | ||
| Chronic kidney disease | 12.83 (5.43–30.30) | <.001 | ||
| Malignancy | 1.82 (0.44–7.51) | .41 | ||
| Chronic liver disease | 1.64 (0.23–11.91) | .63 | ||
| Dementia | 11.15 (6.32–19.69) | <.001 | ||
| Haemoglobin <120 g/L | 5.42 (2.95–9.95) | <.001 | 1.55 (0.81–2.94) | .19 |
| Lymphocyte counts < 0.8 × 109/L | 5.53 (2.85–10.73) | <.001 | 2.46 (1.18–5.11) | .02 |
| Platelet counts < 150 × 109/L | 4.70 (2.53–8.76) | <.001 | 2.60 (1.31–5.19) | .007 |
CCIS: age-adjusted Charlson comorbidity index score; CI: confidence interval; COVID-19: coronavirus disease 2019.