Table 2.

AUC Ratios of cytotoxicity versus TNFα when comparing epitope location

Cell line	CD3 Binder	Format	AUC
			Cytotoxicity	TNFα	Ratio
T0	CD3-H	DbFc	369.1	759.8	0.5
T2	CD3-H	DbFc	394.1	176.4	2.2
T4	CD3-H	DbFc	251.7	0.0
T7	CD3-H	DbFc	197.4	0.0
T0	CD3-M	DbFc	188.6	304.9	0.6
T2	CD3-M	DbFc	188.0	103.3	1.8
T4	CD3-M	DbFc	116.2	0.0
T7	CD3-M	DbFc	91.7	0.0
T0	CD3-H	IgG	330.6	161.0	2.1
T2	CD3-H	IgG	268.0	0.0
T4	CD3-H	IgG	132.9	0.0
T7	CD3-H	IgG	90.5	0.0
T0	CD3-M	IgG	206.0	84.8	2.4
T2	CD3-M	IgG	114.0	0.0
T4	CD3-M	IgG	76.5	0.0
T7	CD3-M	IgG	0.0	0.0