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. 2021 Feb 9;2021:6664453. doi: 10.1155/2021/6664453

Table 2.

1376 innatomic genes were studied in this report, all of which were collected from the InnateDB# (PMID: 23180781).

Classification type Subset Number Percentage
Subcellular location
(5)
Cytoplasm 481 34.96%
Extracellular space 151 10.97%
Nucleus 405 29.43%
Plasma membrane 86 6.25%
Other 253 18.39%

Functional type
(14)
Cytokine 53 3.85%
Enzyme 232 16.86%
G-protein-coupled receptor 22 1.60%
Growth factor 21 1.53%
Ion channel 8 0.58%
Kinase 113 8.21%
Ligand-dependent nuclear receptor 6 0.44%
Other 459 33.36%
Peptidases 54 3.92%
Phosphatase 22 1.60%
Transcription regulator 229 16.64%
Translation regulator 10 0.73%
Transmembrane receptor 88 6.40%
Transporter 59 4.29%

Total 1376 100.00%

#InnateDB is being developed jointly by the Brinkman Laboratory (http://www.brinkman.mbb.sfu.ca) (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (http://cmdr.ubc.ca/bobh/) (University of British Columbia, Vancouver, British Columbia), and the Lynn EMBL Australia Group (http://www.emblaustralia.org/research-leadership/sa-node-lynn-group) (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia). The updated gene list at http://www.innatedb.com provides details of the innatomic genes which have been annotated by either InnateDB or Gene Ontology as having a role in the innatomic response and is updated weekly. Of note, when the list of 1467 genes was used in the Ingenuity Pathway Analysis (IPA), 1376 genes were recognized for classification.