Table 2.
Classification type | Subset | Number | Percentage |
---|---|---|---|
Subcellular location (5) |
Cytoplasm | 481 | 34.96% |
Extracellular space | 151 | 10.97% | |
Nucleus | 405 | 29.43% | |
Plasma membrane | 86 | 6.25% | |
Other | 253 | 18.39% | |
| |||
Functional type (14) |
Cytokine | 53 | 3.85% |
Enzyme | 232 | 16.86% | |
G-protein-coupled receptor | 22 | 1.60% | |
Growth factor | 21 | 1.53% | |
Ion channel | 8 | 0.58% | |
Kinase | 113 | 8.21% | |
Ligand-dependent nuclear receptor | 6 | 0.44% | |
Other | 459 | 33.36% | |
Peptidases | 54 | 3.92% | |
Phosphatase | 22 | 1.60% | |
Transcription regulator | 229 | 16.64% | |
Translation regulator | 10 | 0.73% | |
Transmembrane receptor | 88 | 6.40% | |
Transporter | 59 | 4.29% | |
| |||
Total | 1376 | 100.00% |
#InnateDB is being developed jointly by the Brinkman Laboratory (http://www.brinkman.mbb.sfu.ca) (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (http://cmdr.ubc.ca/bobh/) (University of British Columbia, Vancouver, British Columbia), and the Lynn EMBL Australia Group (http://www.emblaustralia.org/research-leadership/sa-node-lynn-group) (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia). ∗The updated gene list at http://www.innatedb.com provides details of the innatomic genes which have been annotated by either InnateDB or Gene Ontology as having a role in the innatomic response and is updated weekly. Of note, when the list of 1467 genes was used in the Ingenuity Pathway Analysis (IPA), 1376 genes were recognized for classification.