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. 2021 Feb 10;2021:8889313. doi: 10.1155/2021/8889313

Figure 1.

Figure 1

Pulmonary level of MMP-9 is upregulated in the CLP-induced sepsis model. (a) mRNA expression levels of MMP-9 in septic mouse lung tissues. Data were obtained from the following Gene Expression Omnibus datasets: GSE15379, GSE52474, and GSE60088. (b) Mice were subjected to CLP or sham surgery. mRNA and protein expression levels of MMP-9 were verified by RT-PCR and western blotting in lung tissues (n = 7). Representative protein bands were presented on the top of the histograms. Data are presented as the mean ± SEM. p < 0.05 and ∗∗p < 0.01 vs. the control or sham group. MMP-9: matrix metalloproteinase-9; CLP: cecal ligation and puncture.