Table 1.
Ulcer characteristic | Groups | Baseline | First follow-up after 3 months | Second follow-up after 6 months | |||
---|---|---|---|---|---|---|---|
Mean ± standard deviation | P value | Mean ± standard deviation | P value | Mean ± standard deviation | P value | ||
Average size of ulcer | Placebo | 4.75 ± 0.55 | 0.079 | 4.65 ± 0.48 | 0.082 | 4.6 ± 0.50 | <0.0001∗ |
Omega-3 | 5.11 ± 0.70 | 4.37 ± 0.48 | 3.5 ± 1.27 | ||||
Average number of ulcer | Placebo | 2.65 ± 0.81 | 0.06 | 2.45 ± 0.75 | 0.018∗ | 2.45 ± 0.75 | <0.0001∗ |
Omega-3 | 3.6 ± 0.88 | 1.9 ± 0.64 | 1.35 ± 0.67 | ||||
Average duration of ulcer (in weeks) | Placebo | 8.83 ± 1.47 | 0.389 | 8.83 ± 1.47 | <0.0001∗ | 8.57 ± 1.51 | <0.0001∗ |
Omega-3 | 9.69 ± 0.63 | 4.94 ± 0.93 | 3.84 ± 2.03 | ||||
Ulcer free period (in weeks) | Placebo | 3.05 ± 0.68 | 0.07 | 3.1 ± 0.71 | 0.657 | 3.1 ± 0.71 | <0.005∗ |
Omega-3 | 2.55 ± 0.60 | 3.2 ± 0.69 | 3.7 ± 1.94 | ||||
Pain | Placebo | 7.3 ± 1.34 | 1 | 7.2 ± 1.39 | 0.075 | 7.2 ± 1.36 | <0.0001∗ |
Omega-3 | 8.15 ± 1.30 | 4.9 ± 0.96 | 3.65 ± 1.78 | ||||
Mucosal site | Placebo | 4.15 ± 0.93 | 0.474 | 3.75 ± 0.85 | <0.0001∗ | 3.75 ± 0.78 | <0.0001∗ |
Omega-3 | 4.4 ± 1.23 | 2.85 ± 2.3 | 2 ± 1.02 | ||||
USSꞷ (ulcer severity score) | Placebo | 31.1 ± 2.61 | 0.08 | 30.35 ± 2.3 | <0.0001∗ | 30.3 ± 2.29 | <0.0001∗ |
Omega-3 | 33.36 ± 2.02 | 25.75 ± 4.53 | 14.95 ± 6.25 |
∗ P value is significant; ꞷulcer severity score.