Table 1.

Platform dimensions guiding case selection.

Dimension	Platform selection	Rationale
Number of disease groups	Specific group of patients Multiple patient groups	Platforms that might achieve higher levels of patient engagement by pooling resources to support a specific group of target users versus platforms that might have rich resources to target a broader range of users
Disease-related characteristics	Rare disease (eg, amyotrophic lateral sclerosis) Nonprogressive conditions (eg, anxiety disorder, physical disability, diabetes) Progressive conditions (eg, Trajectory 1: steady progress and usually a clear terminal phase such as cancers; Trajectory 2: long-term limitations and gradual decline with intermittent episodes of acute deterioration and some recovery such as organ failure or multiple sclerosis; and Trajectory 3: prolonged gradual decline such as neurological conditions)	Platforms that might achieve higher levels of patient engagement by targeting potential users with high health and information needs