Table 1.
Cohort characteristics.
| Characteristic | Female | Male | Total | P-value |
|---|---|---|---|---|
| No | 151 | 277 | 428 | |
| Age years Mean (SD) | 68.2 (13.3) | 62.0 (15.3) | 64.2 (14.9) | < 0.001* |
| Day 0 25(OH)D ng/ml Mean (SD) | 13.2 (5.7) | 14.4 (10.1) | 13.9 (8.8) | 0.17* |
| SAPS II Mean (SD) | 34.6 (14.7) | 32.7 (15.8) | 33.4 (15.4) | 0.24* |
| Day 0 C-reactive protein μg/mL Mean (SD) | 119.9 (96.4) | 127.6 (86.0) | 124.9 (89.8) | 0.40* |
| Day 0 Procalcitonin ng/ml Median [IQR] | 0.45 [0.14, 1.98] | 0.77 [0.20, 3.02] | 0.66 [0.17, 2.79] | < 0.001† |
| Vitamin D3 Intervention No. (%) | 78 (51.7) | 134 (48.4) | 212 (49.5) | 0.52 |
| Change in 25(OH)D ng/ml Mean (SD) | 11.3 (18.0) | 10.0 (15.5) | 10.4 (16.4) | 0.43* |
| ICU | 0.22 | |||
| Anesthesia ICU No. (%) | 24 (15.9) | 59 (21.3) | 83 (19.4) | |
| Cardiac Surgery ICU No. (%) | 42 (27.8) | 84 (30.3) | 126 (29.4) | |
| Surgical ICU No. (%) | 7 (4.6) | 16 (5.8) | 23 (5.4) | |
| Medicine ICU No. (%) | 31 (20.5) | 59 (21.3) | 90 (21.0) | |
| Neurological ICU No. (%) | 47 (31.1) | 59 (21.3) | 106 (24.8) |
Data presented as No. (%) unless otherwise indicated. P-values determined by chi-square unless designated by (*) then P-value determined by ANOVA or by (†) determined by Kruskal–Wallis test.