Table 1.

RNA-binding proteins involved in translation regulation

RBPs	Protein	Clinical correlates in cancers	Ref
MSI1	Inhibits downstream genes	Maintains the stem cell status	40
MSI2	Promotes Hoxa9, Myc, and Ikzf2	Maintains the self-renewal program of MLL	41
SYNCRIP	Promotes HOXA9 translation	Control myeloid leukemia stem cell program	43
CELF1	Inhibits MYC translation	Inhibits the renew and proliferation of small intestinal epithelial cells	44
HuR	Inhibits Caspase-2L translation	Promotes antiapoptosis of the colorectal cancer cell	45
HuR	Promotes P53 translation	In intestinal cancer cells	46
CPEBs	Inhibits wnt-5a translation regulates polyadenylation	In breast cancer	47
IMP-3	and resulting translation	Facilitates tumorigenesis and metastasis	48
GAIT	promotes IGF-II translation	Promotes tumor proliferation in leukemia	49
	inhibits VEGFA translation	Bone marrow cells under immunotherapy	50