Table 3.
Cox proportional hazard analyses for cardiovascular death in tertiles of FABP4 (n = 721).
| Model 1 | Model 2 | Model 3 | Model 4 | |||||
|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
| FABP4 | ||||||||
| T1 | Reference | – | Reference | – | Reference | – | Reference | – |
| T2 | 2.71 (0.59–12.5) | 0.201 | 2.76 (0.59–12.9) | 0.196 | 2.15 (0.44–10.5) | 0.344 | 2.07 (0.42–10.2) | 0.372 |
| T3 | 4.98 (1.15–21.6) | 0.032 | 5.38 (1.21–23.8) | 0.028 | 4.96 (1.10–22.3) | 0.037 | 4.83 (1.06–21.9) | 0.041 |
| Age (per 1 year) | 1.08 (1.03–1.14) | < 0.001 | 1.09 (1.05–1.13) | < 0.001 | 1.09 (1.04–1.13) | < 0.001 | 1.08 (1.03–1.13) | 0.001 |
| Sex (male) | 1.95 (0.68–5.62) | 0.214 | 1.98 (0.69–5.71) | 0.205 | 2.10 (0.71–6.27) | 0.180 | 2.29 (0.76–6.89) | 0.141 |
| Interaction* | 0.951 | 0.955 | 0.940 | 0.962 | ||||
| Body mass index | – | – | 0.91 (0.86–0.97) | 0.002 | 0.90 (0.85–0.97) | 0.001 | 0.91 (0.86–0.98) | 0.005 |
| BNP (per 1 pg/mL) | – | – | 1.01 (1.00–1.01) | < 0.001 | 1.01 (1.00–1.01) | < 0.001 | 1.01 (1.00–1.01) | < 0.001 |
| hsCRP (per 1 mg/dL) | – | – | – | – | 1.25 (0.01–49.4) | 0.915 | 1.07 (0.01–41.7) | 0.975 |
| Smoking habit | – | – | – | – | – | – | 0.85 (0.27–2.65) | 0.778 |
| Hypertension | – | – | – | – | – | – | 1.89 (0.61–5.81) | 0.267 |
| Diabetes mellitus | – | – | – | – | – | – | 0.44 (0.10–1.94) | 0.281 |
| Dyslipidemia | – | – | – | – | – | – | 0.90 (0.42–1.96) | 0.800 |
| (AIC = 384) | (AIC = 366) | (AIC = 323) | (AIC = 329) | |||||
*Interaction: Sex—FABP4 tertiles.
AIC Akaike's information criterion, BNP brain natriuretic peptide, CI confidence interval, FABP4 fatty acid-binding protein 4, HR hazard ratio, hsCRP high-sensitivity C-reactive protein.