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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Basic Clin Pharmacol Toxicol. 2020 Oct 27;128(3):357–365. doi: 10.1111/bcpt.13515

Figure 2. Exemestane does not affect hERG current density or alter the voltage dependence of activation.

Figure 2.

(A) I-V plot of hERG tail current density during tail voltage protocol with vehicle, 300 nM, and 1 μM exemestane. (B) Bar graphs of peak hERG tail current density at the −20 mV and −100 mV during treatment with exemestane or vehicle. (C) I-V plot of normalized hERG tail current density during an activating voltage protocol with vehicle, 300 nM, and 1 μM exemestane.