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. 2021 Feb 17;12:1098. doi: 10.1038/s41467-021-21286-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a We report correlations between each continuous-valued annotation; diagonal entries are not shown. Numerical results are reported in Supplementary Data 1. b We report estimates of the enrichment/depletion of squared trans-ethnic genetic correlation (λ²(C)), as well as population-specific estimates of heritability enrichment, for quintiles of each continuous-valued annotation. Results are meta-analyzed across 31 diseases and complex traits. Error bars denote ± 1.96 × standard error of the meta-analyzed λ²(C). P-values are obtained from the standard normal distribution. Red stars (⋆) denote two-tailed p < 0.05/40. Numerical results are reported in Supplementary Data 15.